Agreed! However, depending on the size of the amplicon, it is sometimes possible to have species-level resolution with 16S sequencing. Not the case here, as per the figure provided by Irina, the amplicon is quite short (123nt), which is in general insufficient to detect specific pathogens. Even so, genus-level can still be useful to make conclusions like “we found a high relative abundance of genus A, which includes species X and Y, that are detrimental in this body site; to be confirmed if X and Y are really there”.
Anyway, also agree that it is essential to use an algorithm to assign features taxonomy, as manual classification is very time-consuming and prone to error. Besides, it would make all the downstream analyses much more direct and intuitive.
Hope the memory issue is solvable! Good luck