Greetings to all,
I am trying to analyze some data from human fecal samples. From the taxonomic tables obtained I need to compare one single sample against several groups of samples (each group correspond with a group of people with certain condition) and asses if the single sample is clustered whith some group in particular or not (or if it is more simmilar/dissimilar to a certain group). And also, which taxons are differentially abundant between the sample and each group.
Until now, I have performed NMDS and PCoa with Anosim to test the clusters.
My question is: wich statistic test or wich tool should I use to asses which taxons are differentially abundant between the sample and each group?
Could ancom serve for this?
(Also I tested Lefse, but it does not accept one single sample as input to compare).
Any help would be appreciated, kind regards