Hope you guys are doing well under pandemic.
I have a question about the sequencing platform.
As you know, PacBio provides more resolution of taxonomy profiling like species level while MiSeq platform generates only family or genus level taxonomy. Also, MiSeq often showed the inflation of the number of taxa present. However, some researchers worried about the error rate of PacBio platform. I’m also worried about low total number of reads per run in case of PacBio.
Given this condition, which one is generally suggested for normal microbiome analysis?