# Linear Mixed Effect Intrepretation Help

Hi @Tohseef,

This is a big question! Let's try to break it down. You may also find it useful to review linear regression and interpretation if its been a while (a good, basic stats book might be helpful) or talk to a statistician. I've also found this post on Towards Data Science and the parameters section of this post about Stata results helpful at looking at interpretation, but a lot of your questions come down to some regression modeling basics, and there are a lot of really smart people who have invested huge amounts of time into building material teaching these things.

I think the shaded area may be the standard deviation as opposed to the variation, but yes, this is correct.

I'm going to refer you to this article on residual plots, generally. Once again, you have your mean as the solid line, the standard deviation as the shaded area, and the actual values.

Some of this has to do with the way the model is coded here. You could explore the documentation of this particular function to get better control over the modeling.

For this model, and most categorical regression models, you're working against a reference group. Your reference group here is a susceptible mouse from the healthy donor at some theoretical time 0. So, on average, there's a within-group distance of 0.248 [95% CI 0.101, 0.396].

Then, the `genotype[T.wild type]` term asks how much the intercept of your line changes if you have a wild type mouse compares to a susceptible mouse if you hold everything else constant. (Your distance increases by 0.265 [95% CI [0.047, 0.465], which is significant.)

Then, the interaction term, `genotype[T.wild type]:donor[T.pd-1]`, tells us how the slope changes when you've got the `pd-1` donor, compared to when we held things constant, so here, we find that there's a decrease of -0.425 [95% CI -0.723, -0.126] distance units compared to the `genotype[T.wild type]` term alone (which is basically `genotype[T.wild type]:donor[T.hc-1]` because of the way we hold things constant.)

This expands out with the terms.

Now that we've talked through the terms and you've got some resources, Im going to bounce this one back to you.