I wonder if the Qiime2 would have any command for a Hierarchical Feature Engineering (HFE) of OTUs. It would be to select the OTUs before construct the PCoA and run the statistical analysis. Based on what this researcher published Oudah, M., Henschel, A. Taxonomy-aware feature engineering for microbiome classification. BMC Bioinformatics 19, 227 (2018). https://doi.org/10.1186/s12859-018-2205-3
The script is in Python. I would like to know if the Qiime2 has similar tools for that.
Thanks in advance.