Hierarchical Feature Engineering (HFE)

Dear Everyone,

I wonder if the Qiime2 would have any command for a Hierarchical Feature Engineering (HFE) of OTUs. It would be to select the OTUs before construct the PCoA and run the statistical analysis. Based on what this researcher published Oudah, M., Henschel, A. Taxonomy-aware feature engineering for microbiome classification. BMC Bioinformatics 19, 227 (2018). https://doi.org/10.1186/s12859-018-2205-3
The script is in Python. I would like to know if the Qiime2 has similar tools for that.
Thanks in advance.

Hi @AndreFC,
You could check out q2-sample-classifier if you are just looking for a general method for feature selection, and are not particular about the method. This would not take hierarchical taxonomic information into account.

If you want that HFE method, though, it is not implemented in QIIME 2, though it would make an interesting plugin if you or the original authors are interested in building a plugin.

Good luck!

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