I would like to contribute to qiime2 by modifying the q2-vsearch plugin to optionally retain the “UC” file output. As Nicholas, Colin and I previously discussed (original post), the “UC” file is lost upon completion of clustering because it is opened as a tmp file that gets automatically deleted. Since the UC file contains information about who is in each cluster, it could be quite useful to retain, e.g. if one wanted to compare distributional patterns between OTUs and their constituent ASVs.
I think it should be pretty simple to solve this based on our previous discussion. Should I just fork the github repo, test, and make a pull request once I think it’s solved?
Any guidance you can offer about best practices or suggested strategies would be really appreciated!