Maybe it's related to this?
opened 03:45PM - 26 May 19 UTC
**Proposed Behavior**
I think yes, default should be False, but I see both side… s of the argument:
1. True: the `emp-*` methods are designed for EMP, after all. EMP uses golay barcodes (correct?) and hence anyone truly following that protocol would have golay (by default).
2. False: many different primers and barcoding schemes (i.e., non-EMP) are compatible with the "EMP"-style method and I think many novice users will stumble into this, as demonstrated on the [forum](https://forum.qiime2.org/t/plugin-error-from-demux-requres-12nt-instead-8nt/9947?u=nicholas_bokulich). Setting this to default will allow users to decide what they do.
Yeah, that's surprising to me too! I wonder if this is a hold over from the original EMP methods. They are pretty old so there could be some surprises in there!
Could you try this on your data? Hit'em with the double reverse, and report back!
--p-rev-comp-barcodes
--p-rev-comp-mapping-barcodes
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