Hi @Shuxian_LI,
Welcome in the forum!
You can import the sequences as single end sequences, please follow the importing tutorial for that.
(Importing data — QIIME 2 2022.2.0 documentation).
I would suggest using a manifest file, something like:
qiime tools import
--type 'SampleData[SequencesWithQuality]'
--input-path se-33-manifest
--output-path single-end-demux.qza
--input-format SingleEndFastqManifestPhred33V2
Then you can denoise PacBio by using:
https://docs.qiime2.org/2022.2/plugins/available/dada2/denoise-ccs/
Hope it helps.
Cheers
Luca