Hi @cmartino, @mortonjt, and hopefully @fedarko (and sorry if Im wrong),

This is probably a super basic DECOIDE question, but is the underlying Aitchinson distance matrix stable? I’m assuming that if I filter out a sample from the distance matrix, it shouldn’t/won’t affect the other distances? However, I’m also assuming that I need to re-calculate the PCA portion if my underlying sequences change?

Thank you all for the sanity check!