I have run into a snag with VirtualBox (v 6.1.2) suddenly i.e. it was opening and working fine until this morning. When trying to open the qiime2 virtual machine (v2019.10), I received the error message seen in the attached image.
I'm not at all familiar with computer technical troubleshooting, but have tried all the options related to this error I found online (settings>system>uncheck PAE/NX in VB doesn't allow me to OK any changes made and the local PC bios has the VTD enabled already) and still cannot solve the problem.
Any help would be great as I completed 4 datasets worth of analysis yesterday which are on the virtual machine, and today was the day I needed to copy through all my qiime output!
That's the first thing I was going to suggest, so I'm glad you have already checked the bios.
According to this article, there is also a feature inside of Windows that you might have to activate. Can you try that?
It's also possible to install Qiime 2 inside the Windows Subsystem for Linux, which might be a good alternative to the VirtualBox. You got lots of options!
Thanks a bunch! Truth be told, I actually solved the problem about an hour after posting this (coz i never give up, apparently ).... and it's the opposite to what's described in steps 5 and 6 in your link.
For anyone who perhaps needs the fix, it was simple as
finding the turn windows features on and off function in control panel
Unchecking the Hyper-V check box
Reboot
It seems there are some clashing apps that can overwrite the original windows system setup and this checked box needed to be unchecked in this instance.