Hi @ebolyen , In the exit code -11 and .Rprofile thread , I accidentally forgot to include all the .Rprofile info. I also included the .libPaths output you requested. LSB4139A-4DM:~ msullivan$ cat ~/.Rprofile .libPaths(.libPaths()[2])LSB4139A-4DM:~ msullivan$ (qiime2-2017.9) LSB4139A-4DM:~ msulliva…

Thanks @MSullivan ! Based on the .libPaths() output, it looks like the instructions should still generally work. I think what might be wrong is your file doesn't seem to end with a newline. I'm not sure how much that matters to R, but just in case, run the following: echo ".libPaths(.libPaths()[2])…

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.Rprofile and .libPaths with Dada2 exit code -11

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