For the record, I want to add that I reproducibly get this problem after installing q2studio.
Specifically, following the native installation instructions for conda (Natively installing QIIME 2 — QIIME 2 2022.2.0 documentation) for macOs (10.15.7), the cli works as expected. After installing q2studio in the environment, the cli stops working and I get Sergio's error.
I tried both qiime2-2022.2 and qiime2-2021.4, python 3.8.
Hi @Axel_Theorell,
Welcome to the 
forum, thanks for sharing these details!
I suspect this is due to some conflicting dependencies that are installed with q2studio - we aren't actively maintaining this interface, so some of the dependencies for it are most likely older versions of packages that aren't compatible with the newest version(s) of QIIME 2. Unless you are strongly opposed to using the cli, I'd recommend uninstalling q2studio and just using q2cli - this shouldn't produce any dependency issues with reSCRIPT or the latest version of QIIME 2.
Hope this helps!
Cheers 
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