Hello,
I have a question about longitudinal microbiome analysis, in which microbiome data (alpha, beta diversities, and taxa abundance) are considered independent variables. I looked at the current example in Docs, and"Linear Mixed Effect models" and "Volatility analysis" have been suggested for conducting the longitudinal analysis. In those examples, microbiome data have been considered a dependent variable; however, I want to conduct an analysis in which microbiome data (e.g., alpha diversity) is considered an independent variable. Here is an example: Fatigue ~ alpha diversity + age + time
So, I wonder if you could please let me know which longitudinal model best fits my purpose.
Thank you!