is there differece with merge feature-table and not merge

General Discussion
4

Ah ok!

DADA2 builds an error model for each sequencing run, so it's best to run it separately on seperately runs. See this form post and this part of the dada2 tutorial.

For samples on the same run, dada2 should produce equivalent* results wether run on one sample or all!

Let us know if you have any other questions! :raising_hand_man:

EDIT:
*But probably not identical, because

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