Is the Qiime2 feature table compatible with FUNGuild?

Hi @ngonza27,
The example feature table you gave looks a little odd, but I think more or less what is described in this tutorial:

Otherwise you may want to get in touch with the FUNGuild developers to troubleshoot, since they would know their format best.

Note: qiime 1 used biom format in all but the earliest releases... what you describe (a txt document containing an OTU table) is what became known as "classic" OTU tables in qiime 1. The tutorial link above describes how to make a "classic" OTU table.

Good luck!