Is it necessary for the mmevc method to input sequences of microorganisms? How do tax profile from metagenomic sequencing proceed to mmevc?
Hi @18336130937, It shouldn't be a problem to provide a taxonomic profile generated from metagenomic sequencing data. As long as you can get your data into a format that can be imported as FeatureData[Frequency], it should work just fine. For this semantic type, your feature ids can be anything (including taxonomy labels) as long as they are unique, and the data in the table must be counts of features on a per sample basis (relative frequencies won't work here, unfortunately). Some examples of importing into this format can be found here.
If you haven't already, see the QIIME 2 usage instructions in the mmvec README.
Hi @18336130937 yes you can pass in metagenomics proportions directly into MMvec. This is what we did when we analyzed the iHMP dataset in the original paper.
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