I merged these two topics as I suspect they are serving the same goal of getting QIIME 2 working in some fashion.
Re: the problem at hand.
For the one virtualbox that isn’t working, it is it very likely that your processor doesn’t support virtualization, which is why virtualbox is unable to boot Ubuntu correctly. You could try fiddling with various settings in BIOS and inside virtualbox, but we won’t be very much use, since those details are unique to every machine. What CPU is installed in the machine that doesn’t work?
For the windows subsystem, you want to be installing via
apt, that will install QIIME 1, which is not what you want :). Inside the windows subsystem, you can just use these installation instructions and treat it as a linux machine (because it actually is!).