I am newish to QIIME so I apologize if this is a very basic question. I am trying to demultiplex some bacterial data and I have run into the following error message several times:
"Host system reported disk full. VM execution is suspended. You can resume after freeing some space."
The command will run for about 20 minutes before crashing and giving me this error message. I am not sure if it is talking about the disk space on my windows machine or the virtual machine disk space (I am running QIIME through VirtualBox). I have looked at my windows machine disk space and it appears that VirtualBox is using about 118GB of storage, I have no idea why. When I look in deeper it seems that it is the QIIME2 Virtual Disk Image that is using 123,960,320 KB of space. I have no idea what any of this means or how to remedy it. Any advice would be greatly appreciated!