What are the hardware requirements ( RAM etc) for running by qiime vsearch dereplicate-sequences, qiime vsearch cluster-features-de-novo and qiime feature-classifier classify-consensus-vsearch?,
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vsearch dereplicate-sequences and
cluster-features-de-novo take about the same amount of RAM as the reads after they have been dereplicated or clustered according to the coauthor… So I guess the answer is: try it and see if it works! Sometimes 8gb is enough, and sometimes you need more.
classify-consensus-vsearch has to load the database into RAM, so you need roughly as much RAM as the database size.