I am using Deblur for denoising and wonder if anybody knows if it is appropriate or not to merge the outputs from multiple deblur runs?
I have the situation where I have already run Deblur on 2500 sequence libraries, and now am adding some further data (600 sequence libraries).
Do I need to:
a. Re-deblur the whole lot together (2500 + 600 libraries) or
b. Deblur the new 600 and merge with the results of the previously deblur’d 2500?
Thanks in advance to anyone who can provide insight.