dada2 denoise / stats.qza problem

Hi @Anahid_Amani_Moghada,

Thanks for following up with that screenshot! It looks like you have binned quality scores - is your data by chance NovaSeq or iSeq? And do you know if any quality control or filtering have been performed on it prior to your analysis? Check out this related forum post with a similar looking quality plot; if this is the case, you will most likely want to use deblur instead of dada2!

Cheers :lizard: