# \#correlation

**URL:** https://forum.qiime2.org/tag/correlation/157.md

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## [Composition-aware correlation of ASVs from 2 different amplicons](https://forum.qiime2.org/t/composition-aware-correlation-of-asvs-from-2-different-amplicons/32163)

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**Author:** [@salias](https://forum.qiime2.org/u/salias)\
**Replies:** 3\
**Last updated:** [December 20, 2024, 9:34am UTC](https://forum.qiime2.org/t/composition-aware-correlation-of-asvs-from-2-different-amplicons/32163 "2024-12-20T09:34:59Z")

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Hi, I am opening this post (I was missing being the one who asks!) to expose an idea I have had for a project we are finishing in our laboratory. I think it's likely that I'm wrong in some part of my reasoning and that …

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## [Plugin error from SCNIC: 'fastspar'](https://forum.qiime2.org/t/plugin-error-from-scnic-fastspar/30179)

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**Author:** [@Rashmi\_Ira](https://forum.qiime2.org/u/Rashmi_Ira)\
**Replies:** 2\
**Last updated:** [May 19, 2024, 6:15pm UTC](https://forum.qiime2.org/t/plugin-error-from-scnic-fastspar/30179 "2024-05-19T18:15:36Z")

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Hi, @michael.shaffer @eandersk @nhuda6 @llenzi @thermokarst @cquin @arwqiime @mneranjan31 @kohei-108 and other QIIME2 users & developers... I am working on q2-SCNIC tutorial shared by "@michael.shaffer q2-SCNIC: A tool…

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## [The concept of co-occurrence network structure](https://forum.qiime2.org/t/the-concept-of-co-occurrence-network-structure/30030)

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**Author:** [@SingeunOh](https://forum.qiime2.org/u/SingeunOh)\
**Replies:** 3\
**Last updated:** [May 1, 2024, 3:36pm UTC](https://forum.qiime2.org/t/the-concept-of-co-occurrence-network-structure/30030 "2024-05-01T15:36:36Z")

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As below, the spearman value is squared. The original rho value of spearman is -1 to +1 as you know. Does that mean modules appear when the microbiota structure has strong relationship each other disregarding positive …

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## [Using q2-SCNIC or SECOM for correlate taxa and clinical variables](https://forum.qiime2.org/t/using-q2-scnic-or-secom-for-correlate-taxa-and-clinical-variables/28979)

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**Author:** [@tonatiuh](https://forum.qiime2.org/u/tonatiuh)\
**Replies:** 1\
**Last updated:** [January 19, 2024, 11:00pm UTC](https://forum.qiime2.org/t/using-q2-scnic-or-secom-for-correlate-taxa-and-clinical-variables/28979 "2024-01-19T23:00:42Z")

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Hello everyone! :grin: I have been working with QIIME2 for a long time in clinical research, and I have always feared correlations between taxonomic data and the large number of laboratory variables that can be measured …

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## [Is it necessary to transform the read count data into relative abundance form before normalization when analyzing using two different ecosystems (different batches)?](https://forum.qiime2.org/t/is-it-necessary-to-transform-the-read-count-data-into-relative-abundance-form-before-normalization-when-analyzing-using-two-different-ecosystems-different-batches/25979)

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**Author:** [@SingeunOh](https://forum.qiime2.org/u/SingeunOh)\
**Replies:** 2\
**Last updated:** [April 9, 2023, 11:51pm UTC](https://forum.qiime2.org/t/is-it-necessary-to-transform-the-read-count-data-into-relative-abundance-form-before-normalization-when-analyzing-using-two-different-ecosystems-different-batches/25979 "2023-04-09T23:51:56Z")

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Hello! I am considering conducting a correlation analysis using a linear model and a heat map, as well as co-occurrence network analysis using samples from two different body sites in one host. The NGS run for each bod…

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## [How to measure the strength of a correlation between two sample sites](https://forum.qiime2.org/t/how-to-measure-the-strength-of-a-correlation-between-two-sample-sites/22497)

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**Author:** [@mweinroth](https://forum.qiime2.org/u/mweinroth)\
**Replies:** 1\
**Last updated:** [March 19, 2022, 6:19am UTC](https://forum.qiime2.org/t/how-to-measure-the-strength-of-a-correlation-between-two-sample-sites/22497 "2022-03-19T06:19:37Z")

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I am looking for the best tool to provide a paired comparison of beta diversity between one sample site of interest and 9 'preditors'. My experimental setup is as follows: 10 animals were each sampled in ten sites in th…

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## [The best statistical test to analyze the relationship between inflammation markers and microbial abundance](https://forum.qiime2.org/t/the-best-statistical-test-to-analyze-the-relationship-between-inflammation-markers-and-microbial-abundance/12145)

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**Author:** [@cortegas](https://forum.qiime2.org/u/cortegas)\
**Replies:** 7\
**Last updated:** [October 24, 2019, 6:58pm UTC](https://forum.qiime2.org/t/the-best-statistical-test-to-analyze-the-relationship-between-inflammation-markers-and-microbial-abundance/12145 "2019-10-24T18:58:11Z")

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Hey all, I read a forum post where they said that correlation analyses are not the right analysis to measure if there is a relationship between the abundance and other variables (e.g. TNF-alpha). Running a correlation a…

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## [Finding most significant correlations in OTU datasets across multiple groups?](https://forum.qiime2.org/t/finding-most-significant-correlations-in-otu-datasets-across-multiple-groups/9836)

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**Author:** [@emmzee](https://forum.qiime2.org/u/emmzee)\
**Replies:** 6\
**Last updated:** [May 24, 2019, 12:35pm UTC](https://forum.qiime2.org/t/finding-most-significant-correlations-in-otu-datasets-across-multiple-groups/9836 "2019-05-24T12:35:30Z")

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Hi all, Is there any tool to help me find correlation between various types of samples? I have a large OTU dataset (~9k OTUs) and mainly two groups of study. I would like to test for any correlations between those group…

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## [Identifying bacterial taxa (16S) that correlate with eukaryotic taxa (18S)](https://forum.qiime2.org/t/identifying-bacterial-taxa-16s-that-correlate-with-eukaryotic-taxa-18s/8204)

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**Author:** [@rachaellappan](https://forum.qiime2.org/u/rachaellappan)\
**Replies:** 5\
**Last updated:** [February 15, 2019, 1:39am UTC](https://forum.qiime2.org/t/identifying-bacterial-taxa-16s-that-correlate-with-eukaryotic-taxa-18s/8204 "2019-02-15T01:39:26Z")

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Hello, I have a 16S rRNA and an 18S rRNA dataset for the same human faecal samples. The main hypothesis of our study was to identify differences in microbiome composition (bacterial and eukaryotic) between patients and …

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## [Clustering and regression analysis using q2-gneiss](https://forum.qiime2.org/t/clustering-and-regression-analysis-using-q2-gneiss/4211)

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**Author:** [@JenKelly](https://forum.qiime2.org/u/JenKelly)\
**Replies:** 10\
**Last updated:** [June 13, 2018, 7:15pm UTC](https://forum.qiime2.org/t/clustering-and-regression-analysis-using-q2-gneiss/4211 "2018-06-13T19:15:39Z")

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Dear Qiime developers, I am trying to analyse longitudinal data using the q2-gneiss plugin. I have two sets of individuals each consuming a different diet over 5 time points. I am trying to assess the change in microbia…

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## [Are gneiss and q2-longitudinal correlation or regression methods?](https://forum.qiime2.org/t/are-gneiss-and-q2-longitudinal-correlation-or-regression-methods/4307)

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**Author:** [@jjmmii](https://forum.qiime2.org/u/jjmmii)\
**Replies:** 4\
**Last updated:** [May 26, 2018, 5:32am UTC](https://forum.qiime2.org/t/are-gneiss-and-q2-longitudinal-correlation-or-regression-methods/4307 "2018-05-26T05:32:26Z")

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Hey guys, I am reading about how Pearson's correlation can produce false negative results on relative abundances here. This document of R package "compositions" describes four different methods for multivariate analysis…

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## [Any plans to implement Q1 equivalent of "Observation Metadata Correlation"?](https://forum.qiime2.org/t/any-plans-to-implement-q1-equivalent-of-observation-metadata-correlation/2945)

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**Author:** [@vrbana](https://forum.qiime2.org/u/vrbana)\
**Replies:** 3\
**Last updated:** [February 8, 2018, 7:25pm UTC](https://forum.qiime2.org/t/any-plans-to-implement-q1-equivalent-of-observation-metadata-correlation/2945 "2018-02-08T19:25:33Z")

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Perhaps I'm missing something, but I don't currently see a plugin that correlates continuous metadata with features. Thanks!
