I want to compare the microbiota profile of the following stool samples: two groups of mice (KO vs WT), both followed across time (at weeks 3,5,10,20, 56 and 70). How do we perform better the beta div comparison?
We want to see if there are differences at different times between WT and KO (3 vs 3, 5 vs 5, 10 vs 10, and so on). I ckecked the longitudinal tutorial, but I’m not sure about if it fits well to the purpose of the study. I also try to analyze them separately, for example: I generate new variables called Time3, Time5, Time10, etc, with two values: KO or WT, and performed beta-group significance individually on each variable. Is this approach correct? Any advise?
Thanks a lot