statistical analysis

Thanks for developing a great tool! I need some help with statistical analysis. My data set comprises of 45 patients sampled at three different time points at up to six different locations. I now would like to analyze which taxa significantly change over time for each individual at the different locations. I.e. this would be a paired and longitudinal analysis of features. I first looked at qiime longitudinal first-differences but this seems to compare single features such as alpha diversity and not whole feature tables. I then checked out ancom but realized this does not do paired analysis and only compares two states if I understand correctly? Could you please tell me which Qiime2 function/plugin is the correct one to use for my purpose?
Thank you so much for your help!

1 Like

Hi @Stef,
Check out q2-gneiss — sounds like that’s closest to what you are looking for.

Good luck!

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