SSL certificate verify failed error when using RESCRIPt, ask for help

[Nicholas_Bokulich]

Welcome to the forum, @messi!
See this long topic for some insight, starting at this post:

Errors during transaction when installing QIIME2-2019.10

Hey @yanxianl, Based on the first error message, it looks like something went wrong with the TLS handshake, sometimes that's because a server is misconfigured, your OS isn't up to date, or there's a firewall preventing access. The three URLS being downloaded seem to be coming from different hosts (mostly) So my guess is it's a firewall situation. Are you able to click and download those links manually, and do you see anything like a redirect when you do so? That test doesn't help us install…

The bottom line is that this is probably an operating system or firewall issue on your end, and you should talk to your system administrator or IT support to work around this... we can't really troubleshoot since this is not related to RESCRIPt or QIIME 2 directly. Please let us know what you find, though — it may help other forum users who encounter this error

@messi

Now I am using RESCRIPt to download SILVA 138 and wanting to train my own classifier

If you just want to train your own classifier, note that we have shared the RESCRIPt-processed SILVA files ready for classifier training (and trained classifiers) here:
https://docs.qiime2.org/2020.6/data-resources/

Good luck!