I am having the similar trouble issue as described in this thread when installing RESCRIPt.
I sucessfully installed it inside my qiime2-2022.2 environment using the commands described on the github page
pip install git+https://github.com/bokulich-lab/RESCRIPt.git
The message I got after reads:
DEPRECATION: Python 2.7 reached the end of its life on January 1st, 2020. Please upgrade your Python as Python 2.7 is no longer maintained. pip 21.0 will drop support for Python 2.7 in January 2021. More details about Python 2 support in pip can be found at https://pip.pypa.io/en/latest/development/release-process/#python-2-support pip 21.0 will remove support for this functionality. Collecting git+https://github.com/bokulich-lab/RESCRIPt.git Cloning https://github.com/bokulich-lab/RESCRIPt.git to /private/var/folders/c7/b0nwnl650c35n5gzff7x80b80000gn/T/pip-req-build-XPe8XM Running command git clone -q https://github.com/bokulich-lab/RESCRIPt.git /private/var/folders/c7/b0nwnl650c35n5gzff7x80b80000gn/T/pip-req-build-XPe8XM Requirement already satisfied (use --upgrade to upgrade): rescript==2021.11.0+3.g8aa880e from git+https://github.com/bokulich-lab/RESCRIPt.git in /Library/Frameworks/Python.framework/Versions/2.7/lib/python2.7/site-packages Building wheels for collected packages: rescript Building wheel for rescript (setup.py) ... done Created wheel for rescript: filename=rescript-2021.11.0+3.g8aa880e-py2-none-any.whl size=232613 sha256=6c18a41d423dfb7e4a834fa88bb713233c99c5dcac1ded5ea1e4d547e8a0418f Stored in directory: /private/var/folders/c7/b0nwnl650c35n5gzff7x80b80000gn/T/pip-ephem-wheel-cache-u8nqTi/wheels/75/19/eb/fc5387ec465bf16c772c05fe259075e927a9ccfd3925c4dc28 Successfully built rescript
However when I try run qiime rescript I get ther error:
Error: QIIME 2 has no plugin/command named 'rescript'.
I tried all different options described in the above discusssion threads but with no luck. I would really appreciate any guidance! Thank you.