# plugin error from phylogeny raxml (default): returned non-zero exit status 255 **URL:** https://forum.qiime2.org/t/plugin-error-from-phylogeny-raxml-default-returned-non-zero-exit-status-255/24765 **Category:** Technical Support **Tags:** phylogeny, raxml **Created:** [November 15, 2022, 3:07pm UTC](https://forum.qiime2.org/t/plugin-error-from-phylogeny-raxml-default-returned-non-zero-exit-status-255/24765 "2022-11-15T15:07:33Z") **Posts on this page:** 1 **Showing post:** 2
### Author: ![SoilRotifer](https://forum.qiime2.org/user_avatar/forum.qiime2.org/soilrotifer/32/21071_2.png) [@SoilRotifer](https://forum.qiime2.org/u/SoilRotifer) #### Post date: [November 15, 2022, 5:09pm UTC](https://forum.qiime2.org/t/plugin-error-from-phylogeny-raxml-default-returned-non-zero-exit-status-255/24765/2 "2022-11-15T17:09:58Z")
Hi @Shuqi, If you scroll through the error message you'll see this: > [@Shuqi](#): > > ```auto > The file /var/folders/wr/wy2g8g411gd5l7rzddpf7f8r0000gn/T/qiime2/sl/data/17008f74-c8c9-4634-b422-572865c743d8/data/aligned-dna-sequences.fasta.reduced RAxML wants to open for writing or appending can not be opened [mode: wb], exiting ... > > ``` This tells me that your account is not allowed to write to this path. Assuming you are running Mac OS X, I am thinking it might be related to this issue: > [@QIIME 2 2022.8 is now available!](https://forum.qiime2.org/t/qiime-2-2022-8-is-now-available/23994/10): > > Hey everyone! We've just updated our release with a fix for OS X which would produce errors such as: ValueError: Path: 'None' already exists and is not a cache This release has been a trial-by-fire for a new feature that will be officially announced in November, called "Artifact Cache". We're sorry for the bumpy ride, but appreciate everyone's patience as we iron out these issues. Briefly, this occured because we now create a single directory structure in your $TMPDIR instead of littering it… Perhaps re-install the latest patched version of 2022.8? Does anyone else have any thoughts? -Mike --- _[View the full topic](https://forum.qiime2.org/t/plugin-error-from-phylogeny-raxml-default-returned-non-zero-exit-status-255/24765)._