Plugin error from dada2: An error was encountered while running DADA2 in R

[colinbrislawn (Colin J Brislawn)]

I think I know what is the issue is! Even though your error is happening in the chimera removal step, the issue may be about the number of input reads for step 2.

@Mehrbod_Estaki

About 100,000 reads (which is the min default) is recommended for this step. That is not to say the process will not finish, it is that we don’t know whether the error model fits the data well enough.

When you run this same command on a larger data set, does the plugin complete OK?

EDIT: If you have a small data set, check out Deblur. It comes with a pre-build error model so no training is needed.