# Pick up a Right Alignemnt Method. **URL:** https://forum.qiime2.org/t/pick-up-a-right-alignemnt-method/17799 **Category:** General Discussion **Created:** [December 15, 2020, 12:21pm UTC](https://forum.qiime2.org/t/pick-up-a-right-alignemnt-method/17799 "2020-12-15T12:21:33Z") **Posts on this page:** 1 **Showing post:** 5
### Author: ![TurboQiimer](https://forum.qiime2.org/letter_avatar_proxy/v4/letter/t/46a35a/32.png) [@TurboQiimer](https://forum.qiime2.org/u/TurboQiimer) #### Post date: [December 17, 2020, 4:30pm UTC](https://forum.qiime2.org/t/pick-up-a-right-alignemnt-method/17799/5 "2020-12-17T16:30:08Z")
BLAST is a popular tool in NCBI website. There is no any doubt that it is a useful and effective tool in alignment, but based on survey in Qiime2 forum, I recognized Vesearch is widely used in classification. I read the two papers you suggested to me. The part I needed was mentioned in mathematics or algorithmic way, that I could not catch more. Yeah... you are right! I want simply to know which one is the best, Vesrach or Blast, although [it sounds BLAST output represents that it works well in my case!](https://forum.qiime2.org/t/duel-of-blast-vesearch-classifiers/17777) I am just in dilemma, indeed! Thanks your guidence in advance. Qiimer --- _[View the full topic](https://forum.qiime2.org/t/pick-up-a-right-alignemnt-method/17799)._