# MAFFT Error: non-zero exit status 1

**URL:** https://forum.qiime2.org/t/mafft-error-non-zero-exit-status-1/6345
**Category:** User Support
**Tags:** mafft
**Created:** [October 6, 2018, 2:37am UTC](https://forum.qiime2.org/t/mafft-error-non-zero-exit-status-1/6345 "2018-10-06T02:37:17Z")
**Posts on this page:** 1
**Showing post:** 3

<div class="post-metadata">

### Author: ![ebolyen](https://forum.qiime2.org/user_avatar/forum.qiime2.org/ebolyen/32/11_2.png) [@ebolyen](https://forum.qiime2.org/u/ebolyen)
#### Post date: [October 9, 2018, 5:47pm UTC](https://forum.qiime2.org/t/mafft-error-non-zero-exit-status-1/6345/3 "2018-10-09T17:47:24Z")

</div>

Hey @Purrsia_Felidae,

Funny you should mention alternative aligners, @epruesse is working on a SINA aligner as we speak, however given the size of your dataset (and assuming your ultimate goal for alignment is to generate a phylogeny), you could try using a SEPP algorithm provided by this plugin:

[https://github.com/biocore/q2-fragment-insertion](https://github.com/biocore/q2-fragment-insertion)

* * *

Of course, we could always use more help, so if you have a bit of Python experience, you could always create some PRs for q2-alignment adding more (or even create your own plugin which does whatever you want).

---

_[View the full topic](https://forum.qiime2.org/t/mafft-error-non-zero-exit-status-1/6345)._