# Is there a way to install PICRUSt2 in Apple chip M2 **URL:** https://forum.qiime2.org/t/is-there-a-way-to-install-picrust2-in-apple-chip-m2/25554 **Category:** PICRUSt2 **Tags:** picrust **Created:** [February 20, 2023, 9:39am UTC](https://forum.qiime2.org/t/is-there-a-way-to-install-picrust2-in-apple-chip-m2/25554 "2023-02-20T09:39:49Z") **Posts on this page:** 9 **Page:** 1
### Author: ![otrujillor](https://forum.qiime2.org/user_avatar/forum.qiime2.org/otrujillor/32/14063_2.png) [@otrujillor](https://forum.qiime2.org/u/otrujillor) #### Post date: [February 20, 2023, 9:39am UTC](https://forum.qiime2.org/t/is-there-a-way-to-install-picrust2-in-apple-chip-m2/25554/1 "2023-02-20T09:39:49Z")
Hello, everyone, I'm having trouble installing PICRUSt on the latest version of QIIME2 on my MacBook with the new Apple M2 chip. I've already tried downgrading to an earlier version of QIIME2, but the plugin still isn't compatible (it says _**mach-o file, but is an incompatible architecture (have (arm64), need (x86\_64)**_). Does anyone know if there is a way to install PICRUSt on the latest version of QIIME2 with the new Apple M2 chip? Any advice or guidance would be greatly appreciated. ---
### Author: ![crusher083](https://forum.qiime2.org/user_avatar/forum.qiime2.org/crusher083/32/9597_2.png) [@crusher083](https://forum.qiime2.org/u/crusher083) #### Post date: [February 20, 2023, 9:48am UTC](https://forum.qiime2.org/t/is-there-a-way-to-install-picrust2-in-apple-chip-m2/25554/2 "2023-02-20T09:48:22Z")
Hello, no, there is no way to install it. The packages should be explicitly developed for different arches, and PICRUSt2 wasn't. Cheers V ---
### Author: ![otrujillor](https://forum.qiime2.org/user_avatar/forum.qiime2.org/otrujillor/32/14063_2.png) [@otrujillor](https://forum.qiime2.org/u/otrujillor) #### Post date: [February 20, 2023, 10:09am UTC](https://forum.qiime2.org/t/is-there-a-way-to-install-picrust2-in-apple-chip-m2/25554/3 "2023-02-20T10:09:47Z")
Thank you so much for your quick response. ![Captura de pantalla 2023-02-20 a la(s) 3.05.55](https://forum-qiime2-org.s3.dualstack.us-west-2.amazonaws.com/original/2X/e/e46af30fe7c644c5bb83fdc20d1ce13ad408c8b0.jpeg) Now it makes sense. I was getting that error message. I have read that there is a way to install PICRUSt2 alone without QIIME2, I will try to do that, I will look for a tutorial or something. If someone knows, please let me know. Thanks ---
### Author: ![crusher083](https://forum.qiime2.org/user_avatar/forum.qiime2.org/crusher083/32/9597_2.png) [@crusher083](https://forum.qiime2.org/u/crusher083) #### Post date: [February 20, 2023, 10:36am UTC](https://forum.qiime2.org/t/is-there-a-way-to-install-picrust2-in-apple-chip-m2/25554/4 "2023-02-20T10:36:31Z")
picrust2 has a nifty instruction on GitHub ([Full pipeline script · picrust/picrust2 Wiki · GitHub](https://github.com/picrust/picrust2/wiki/Full-pipeline-script)). You can load results of predictions as `FeatureTable[Frequency]` afterward. From what I see on bioconda, it should work on arm64. ---
### Author: ![otrujillor](https://forum.qiime2.org/user_avatar/forum.qiime2.org/otrujillor/32/14063_2.png) [@otrujillor](https://forum.qiime2.org/u/otrujillor) #### Post date: [February 20, 2023, 8:09pm UTC](https://forum.qiime2.org/t/is-there-a-way-to-install-picrust2-in-apple-chip-m2/25554/5 "2023-02-20T20:09:42Z")
> [@crusher083](#): > > it should work on arm64. Thank you so much. I Installed PICRUSt2 as standalone, and it worked. Thanks. ---
### Author: ![lovely\_chimera](https://forum.qiime2.org/user_avatar/forum.qiime2.org/lovely_chimera/32/16870_2.png) [@lovely\_chimera](https://forum.qiime2.org/u/lovely_chimera) #### Post date: [October 12, 2023, 3:06pm UTC](https://forum.qiime2.org/t/is-there-a-way-to-install-picrust2-in-apple-chip-m2/25554/6 "2023-10-12T15:06:40Z")
Hello I'm also using Macbook with M2 chip. How did you install Picrust2? What do you mean by standalone installation? ---
### Author: ![cherman2](https://forum.qiime2.org/user_avatar/forum.qiime2.org/cherman2/32/17129_2.png) [@cherman2](https://forum.qiime2.org/u/cherman2) #### Post date: [October 12, 2023, 4:16pm UTC](https://forum.qiime2.org/t/is-there-a-way-to-install-picrust2-in-apple-chip-m2/25554/7 "2023-10-12T16:16:45Z")
Hi @lovely_chimera Picrust2 is a software that can be used by itself and within QIIIME 2. Seems like right now the only way to use it is to use it not within QIIME 2 if you have an M2 chip. Follow the github link above and it should have install instructions for how to download Picrust2 outside of QIIME 2. Hope that helps! ---
### Author: ![otrujillor](https://forum.qiime2.org/user_avatar/forum.qiime2.org/otrujillor/32/14063_2.png) [@otrujillor](https://forum.qiime2.org/u/otrujillor) #### Post date: [October 24, 2023, 9:21pm UTC](https://forum.qiime2.org/t/is-there-a-way-to-install-picrust2-in-apple-chip-m2/25554/11 "2023-10-24T21:21:08Z")
> [@cherman2](#): > > Seems like right now the only way to use it is to use it not within QIIME 2 if you have an M2 chip. Hi @cherman2, q2-picrust2 has recently launched an update. Now it is possible to install it in chip M1/M2. More info in Qiime2 plugins section: [https://library.qiime2.org/plugins/q2-picrust2/13/](https://library.qiime2.org/plugins/q2-picrust2/13/) ---
### Author: ![cherman2](https://forum.qiime2.org/user_avatar/forum.qiime2.org/cherman2/32/17129_2.png) [@cherman2](https://forum.qiime2.org/u/cherman2) #### Post date: [October 24, 2023, 9:24pm UTC](https://forum.qiime2.org/t/is-there-a-way-to-install-picrust2-in-apple-chip-m2/25554/12 "2023-10-24T21:24:00Z")
Thanks for the update @otrujillor!