Hi. I was working with the command " qiime dada2 denoised paired" and this is the arguments that I wrote
time qiime dada2 denoise-paired
--i-demultiplexed-seqs paired-end-demux.qza \
Hello @839536300, you appear to be having the same issue as this post which we, unfortunately, don't seem to have a real solution for yet, but there are some suggestions in that thread that might help you, and if we do figure out exactly what's happening, the solution will most likely be posted in that thread.