Hi @Mehrdad,
Thanks! So if I’m not mistaken I believe your MemoryError indicates that you have insufficient RAM for this task. This is pretty common with the Silva dataset due to its size. You can browse around the forum to see what others have done, for ex here. Ultimately you just need access to more RAM. If that is not an option for you then you could try the Greengenes database which is a lot less memory intensive.
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