I forgot that the issue outlined here appears to have been fixed in qiime2-2020.11. So you should be fine.
However, if you ever run into a case in which you need to re-orient your sequences you can use RESCRIPt's orient-seqs
command.
EDIT: I forgot that the orient-seqs
command will currently only run on FASTA inputs. We hope to work on a solution for FASTQ.
-Mike