I would like to perform denoising for my data which are seqs.fna files, so I’m not sure how to start with them?
Unfortunately, denoising is not possible — denoising in QIIME 2 relies on the presence of quality scores in FASTQ data, so this is not possible on FASTA (.fna).
You can still perform OTU clustering on these data, following this tutorial.
I hope that helps!
Thank you for your response.
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