Denoising and trimming already demultiplexed paired end data

Having just gone through this steps recently myself I thought I’d share quick tip. You can quickly find the absolute paths to your files that you need in the manifest file with:

find 'pwd' /path/to/your/folder/containing/fastqs .htaccess

That lists the absolute paths of all samples that you can easily copy & paste into your csv manifest file. Beats doing them one by one.

I’m sure it wouldn’t be too hard scripting the manifest creation process from files in a target folder but this is easy as well.

On another related note, is it possible to create a fastq variant detection script in the event that you don’t know where the inherited files have come from?

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