# Conda install fails macOS 12.5.1

**URL:** https://forum.qiime2.org/t/conda-install-fails-macos-12-5-1/23961
**Category:** Technical Support
**Tags:** install
**Created:** [August 23, 2022, 2:19pm UTC](https://forum.qiime2.org/t/conda-install-fails-macos-12-5-1/23961 "2022-08-23T14:19:09Z")
**Posts on this page:** 4
**Page:** 1

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### Author: ![Zach\_Burcham](https://forum.qiime2.org/user_avatar/forum.qiime2.org/zach_burcham/32/18784_2.png) [@Zach\_Burcham](https://forum.qiime2.org/u/Zach_Burcham)
#### Post date: [August 23, 2022, 2:19pm UTC](https://forum.qiime2.org/t/conda-install-fails-macos-12-5-1/23961/1 "2022-08-23T14:19:09Z")

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Hello,

I just got a new computer (MacBook Pro M1 2021) and am trying to install Qiime2 2022.2 with conda. When I run:

conda env create -n qiime2-2022.2 --file qiime2-2022.2-py38-osx-conda.yml

I get:

Collecting package metadata (repodata.json): done  
Solving environment: failed

ResolvePackageNotFound:

- bioconductor-iranges=2.28.0
- pbzip2=1.1.13
- bioconductor-shortread=1.52.0
- q2-diversity-lib=2022.2.1
- q2-gneiss=2022.2.0
- blast=2.12.0
- isa-l=2.30.0
- q2templates=2022.2.0
- perl-scalar-list-utils=1.62
- gfortran\_osx-64=9.3.0
- q2-quality-filter=2022.2.0
- libgcc=4.8.5
- q2-phylogeny=2022.2.0
- q2-types=2022.2.0
- htslib=1.15.1
- r-rcurl=1.98\_1.6
- q2-alignment=2022.2.0
- q2-mystery-stew=2022.2.0
- q2-emperor=2022.2.0
- bowtie2=2.4.5
- xopen=1.5.0
- q2-diversity=2022.2.1
- perl-encode=3.17
- cutadapt=4.0
- q2-fragment-insertion=2022.2.0
- dnaio=0.9.0
- gfortran\_impl\_osx-64=9.3.0
- bioconductor-biocparallel=1.28.3
- bioconductor-rsamtools=2.10.0
- sortmerna=2.0
- q2-feature-classifier=2022.2.0
- perl-pathtools=3.75
- perl-compress-raw-zlib=2.105
- bioconductor-delayedarray=0.20.0
- q2-longitudinal=2022.2.0
- bioconductor-zlibbioc=1.40.0
- scikit-bio=0.5.6
- bioconductor-biostrings=2.62.0
- r-jpeg=0.1\_9
- sepp=4.3.10
- bioconductor-xvector=0.34.0
- bioconductor-s4vectors=0.32.3
- fasttree=2.1.10
- unifrac=0.20.3
- q2-cutadapt=2022.2.0
- q2-deblur=2022.2.0
- pandoc=2.18
- bioconductor-genomicranges=1.46.1
- mafft=7.505
- entrez-direct=16.2
- q2-feature-table=2022.2.0
- q2-metadata=2022.2.0
- q2-taxa=2022.2.0
- bioconductor-rhtslib=1.26.0
- perl-compress-raw-bzip2=2.103
- iqtree=2.2.0\_beta
- python-isal=0.11.1
- q2galaxy=2022.2.0
- q2-vsearch=2022.2.0
- q2-dada2=2022.2.0
- bioconductor-genomicalignments=1.30.0
- libgfortran5=9.3.0
- r-vegan=2.6\_2
- emperor=1.0.3
- q2-sample-classifier=2022.2.0
- qiime2=2022.2.1
- q2-demux=2022.2.0
- perl-list-moreutils-xs=0.430
- raxml=8.2.12
- q2-quality-control=2022.2.0
- vsearch=2.7.0
- fastcluster=1.2.6
- q2cli=2022.2.0
- bioconductor-dada2=1.22.0
- biom-format=2.1.10
- q2-composition=2022.2.0
- perl-json-xs=2.34
- bioconductor-biobase=2.54.0
- hmmer=3.1b2
- perl-io-compress=2.106
- samtools=1.15.1

Any idea what might be causing this?

Thanks,  
Zach

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### Author: ![colinbrislawn](https://forum.qiime2.org/user_avatar/forum.qiime2.org/colinbrislawn/32/6221_2.png) [@colinbrislawn](https://forum.qiime2.org/u/colinbrislawn)
#### Post date: [August 24, 2022, 12:03am UTC](https://forum.qiime2.org/t/conda-install-fails-macos-12-5-1/23961/2 "2022-08-24T00:03:35Z")

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Hey Zach,

I've also got an M1 mac and, unfortunately, bioconda does not ship native builds for the osx-arm64 processors inside of these things.

Here's the workaround we have right now:

> [@Install QIIME2 on Macbook Pro 2021 with apple M1 Chip](https://forum.qiime2.org/t/install-qiime2-on-macbook-pro-2021-with-apple-m1-chip/21492):
>
> Install miniforge3; Set the Terminal app to run under rosetta mode; Use the command line below to install qiime2 with the library link to osx-64 for intel Chip; CONDA\_SUBDIR=osx-64 conda env create -n qiime2-2021.11 --file qiime2-2021.11-py38-osx-conda.yml After qiime2 installation, a dialogue will show and suggests to install x-run. Please choose "yes"; Use the command line below to activate the qiime2 environment and set the library link to the intel chip subdirectory; cond…

* * *

The future looks bright: lots of software run great on the new Apple silicon and conda-forge already [ships native osx-arm64 builds](https://conda-forge.org/blog/posts/2020-10-29-macos-arm64/).

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<div class="post-metadata">

### Author: ![Zach\_Burcham](https://forum.qiime2.org/user_avatar/forum.qiime2.org/zach_burcham/32/18784_2.png) [@Zach\_Burcham](https://forum.qiime2.org/u/Zach_Burcham)
#### Post date: [August 24, 2022, 3:05pm UTC](https://forum.qiime2.org/t/conda-install-fails-macos-12-5-1/23961/3 "2022-08-24T15:05:54Z")

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Perfect, thank you Colin

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<div class="post-metadata">

### Author: ![system](https://forum-qiime2-org.s3.dualstack.us-west-2.amazonaws.com/original/3X/2/1/21af5fe23cb6f4579467c66a9ed94e55274ca7bd.svg) [@system](https://forum.qiime2.org/u/system)
#### Post date: [September 24, 2022, 9:06pm UTC](https://forum.qiime2.org/t/conda-install-fails-macos-12-5-1/23961/4 "2022-09-24T21:06:19Z")

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