# Attempt to install Qiime2 with Pixi on an M1 mac
**URL:** https://forum.qiime2.org/t/attempt-to-install-qiime2-with-pixi-on-an-m1-mac/33491
**Category:** Developer Discussion
**Tags:** conda
**Created:** [July 23, 2025, 6:15am UTC](https://forum.qiime2.org/t/attempt-to-install-qiime2-with-pixi-on-an-m1-mac/33491 "2025-07-23T06:15:08Z")
**Posts on this page:** 3
**Page:** 1
### Author:  [@colinbrislawn](https://forum.qiime2.org/u/colinbrislawn)
#### Post date: [July 23, 2025, 6:15am UTC](https://forum.qiime2.org/t/attempt-to-install-qiime2-with-pixi-on-an-m1-mac/33491/1 "2025-07-23T06:15:08Z")
I downloaded a yml file and converted it to the pixi format:
```auto
wget https://raw.githubusercontent.com/qiime2/distributions/refs/heads/dev/2025.7/amplicon/released/qiime2-amplicon-macos-latest-conda.yml
pixi init --import qiime2-amplicon-macos-latest-conda.yml
```
I edited this part:
```auto
platforms = ["osx-64"]
```
Then `pixi install`
Miraculously, it made it through the install but missed some R software, including the historic problem `bioconductor-genomeinfodb`
So close!
🧚 😿
---
### Author:  [@ebolyen](https://forum.qiime2.org/u/ebolyen)
#### Post date: [July 23, 2025, 6:58pm UTC](https://forum.qiime2.org/t/attempt-to-install-qiime2-with-pixi-on-an-m1-mac/33491/2 "2025-07-23T18:58:23Z")
Interesting, do they not run post-link hooks? That's where our nemesis lives.
EDIT: check out this:
> **[Pixi Configuration - Pixi by prefix.dev](https://pixi.sh/dev/reference/pixi_configuration/#run-post-link-scripts)**
>
> Pixi Documentation — Next-gen package manager for reproducible development setups
That might solve it.
---
### Author:  [@colinbrislawn](https://forum.qiime2.org/u/colinbrislawn)
#### Post date: [April 8, 2026, 1:53pm UTC](https://forum.qiime2.org/t/attempt-to-install-qiime2-with-pixi-on-an-m1-mac/33491/3 "2026-04-08T13:53:02Z")
I tried again, and this time it works!
```sh
wget https://raw.githubusercontent.com/qiime2/distributions/refs/heads/dev/2026.4/amplicon/passed/qiime2-amplicon-osx-64-conda.yml
```
```sh
pixi init --platform osx-64 --import qiime2-amplicon-osx-64-conda.yml
✔ Created /Users/colin/bin/github/pixi_demo/pixi.toml
```
```sh
pixi run qiime info
System versions
Python version: 3.12.13
QIIME 2 release: 2026.4
QIIME 2 version: 2026.4.0.dev0+26.gaa5ccc3
q2cli version: 2026.4.0.dev0+2.gcfcff79
Installed plugins
alignment: 2026.4.0.dev0+2.g135b02f
boots: 2026.4.0.dev0+9.g4cef47f
composition: 2026.4.0.dev0+9.g141c1b8
cutadapt: 2026.4.0.dev0+1.g52eff68
dada2: 2026.4.0.dev0
deblur: 2026.4.0.dev0
demux: 2026.4.0.dev0
diversity: 2026.4.0.dev0+11.g8c16985
diversity-lib: 2026.4.0.dev0+1.g94fd703
emperor: 2026.4.0.dev0
feature-classifier: 2026.4.0.dev0+7.ga3e1796
feature-table: 2026.4.0.dev0+2.g7ecfa15
fondue: 2026.4.0.dev0+2.gb87ab61
fragment-insertion: 2026.4.0.dev0
kmerizer: 2026.4.0.dev0
longitudinal: 2026.4.0.dev0+1.g9f21820
metadata: 2026.4.0.dev0
phylogeny: 2026.4.0.dev0+3.g5446684
quality-control: 2026.4.0.dev0
quality-filter: 2026.4.0.dev0
rescript: 2026.4.0.dev0+16.g72292cd
sample-classifier: 2026.4.0.dev0+3.g802233e
stats: 2026.4.0.dev0
taxa: 2026.4.0.dev0
types: 2026.4.0.dev0+1.gaba63b0
vizard: 2026.4.0.dev0+1.gf997d5b
vsearch: 2026.4.0.dev0+1.g67f9c86
Application config directory
/Users/colin/bin/github/q2-forums/.pixi/envs/default/var/q2cli
Config
Config Source: /Users/colin/bin/github/q2-forums/.pixi/envs/default/etc/qiime2_config.toml
Getting help
To find help and learning resources, visit https://qiime2.org.
To get help with configuring and/or understanding QIIME 2 parallelization, visit https://use.qiime2.org/en/stable/references/parallel-configuration.html
```
I'll test it out more and see if it can replace conda
🐍 📦 🧚